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Phenotypes Associated with This Genotype
Genotype
MGI:3576481
Allelic
Composition
Airetm1Mmat/Airetm1Mmat
Genetic
Background
C.Cg-Airetm1Mmat
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Airetm1Mmat mutation (1 available); any Aire mutation (52 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• exhibited similar autoimmune phenotypes as seen in the mixed C57BL/6 and CBA background
• Background Sensitivity: demonstrated strong auto-antibodies against gastric mucosa

digestive/alimentary system
• Background Sensitivity: lymphoid cell infiltration in the gastric mucosa

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
autoimmune polyendocrine syndrome type 1 DOID:0050167 OMIM:240300
J:96580


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory