Analysis Tools
mortality/aging
|
• more than 80% lethality before weaning due to unknown causes, survivors are viable
|
hematopoietic system
|
• thymocytes reduced to about 5% of controls but peripheral single positive cell populations remained in normal range
|
|
• megakaryocyte hyperplasia in bone marrow with corresponding reductions in other bone marrow elements
|
anisocytosis
(
J:98329
)
|
• erythrocytes of variable size
|
|
• thrombocytosis and increased numbers of megakaryocytes in circulation
|
growth/size/body
|
• body size was 50-70% of controls at 4 weeks of age
|
immune system
|
• thymocytes reduced to about 5% of controls but peripheral single positive cell populations remained in normal range
|
endocrine/exocrine glands
|
• thymocytes reduced to about 5% of controls but peripheral single positive cell populations remained in normal range
|
