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Phenotypes Associated with This Genotype
Genotype
MGI:3579126
cx5
Allelic
Composition		 Gata1tm1Phi/Gata1+
Tg(HBB-Gata1)G4Phi/0
Genetic
Background		 involves: FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm1Phi mutation (0 available); any Gata1 mutation (45 available)
Tg(HBB-Gata1)G4Phi mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal erythropoiesis ( J:98277 )
• the onset of definitive erythropoiesis is delayed with a lower ratio of definitive to primitive erythroid cells at E13.5 and E14.0
• differentiation of erythroid progenitors in the hanging drop assay is intermediate between wild-type mice and males hemizygous for Tg(HBB-Gata1)G4Phi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory