Phenotypes Associated with This Genotype

Genotype
MGI:3579805

• Allelic Composition: Ccl3^tm1Unc/Ccl3⁺; Hexb^tm1Rlp/Hexb^tm1Rlp
• Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:90687 )

• life span of approximately 138 day

behavior/neurological

abnormal motor coordination/balance ( J:90687 )

• improved performance on a rotarod compared to mice homozygous for the Hexb allele alone

abnormal righting response ( J:90687 )

• improved relative to mice homozygous for the Hexb allele alone

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Sandhoff disease		DOID:3323	OMIM:268800	J:90687