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Phenotypes Associated with This Genotype
Genotype
MGI:3580056
Allelic
Composition		 Nf1tm1Tyj/Nf1+
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nf1tm1Tyj mutation (3 available); any Nf1 mutation (161 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal spatial learning ( J:38703 )
• impairment in Morris Water Maze that was overcome with extensive training, however normal long term memory in cued fear conditioning test and normal nociception

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
neurofibromatosis 1 DOID:0111253 OMIM:162200
 J:38703

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory