Phenotypes Associated with This Genotype

Genotype
MGI:3580297

cn5

• Allelic Composition: Stk11^tm1Keis/Stk11^tm1Keis; Tg(Ckmm-cre)5Khn/0
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

decreased muscle cell glucose uptake ( J:98513 )

• block of glucose uptake stimulated by 5-aminoimidazole-4-caroboxamide (AICAR) or by muscle contraction, but not by insulin

• possessed normal fasted and fed blood glucose levels

reproductive system

male infertility ( J:98513 )

♂ • homozygous male mice are infertile, female are fertile

growth/size/body

growth/size/body region phenotype ( J:98513 )

N • normal growth from 4 to 10 weeks of age

cellular

decreased muscle cell glucose uptake ( J:98513 )

• block of glucose uptake stimulated by 5-aminoimidazole-4-caroboxamide (AICAR) or by muscle contraction, but not by insulin

• possessed normal fasted and fed blood glucose levels