Phenotypes Associated with This Genotype

Genotype
MGI:3580872

hm1

• Allelic Composition: Sod2^tm1.1Kskk/Sod2^tm1.1Kskk
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:98289 )

• die 8 -10 days after birth

cardiovascular system

abnormal myocardial fiber morphology ( J:98289 )

• extensive lipid peroxidation is seen in the myocardium at 3 days after birth

growth/size/body

postnatal growth retardation ( J:98289 )

• severe growth retardation

behavior/neurological

fatigue ( J:98289 )

• fatigue rapidly

cellular

oxidative stress ( J:98289 )

• extensive lipid peroxidation is seen in the myocardium at 3 days after birth

muscle

abnormal myocardial fiber morphology ( J:98289 )

• extensive lipid peroxidation is seen in the myocardium at 3 days after birth