Phenotypes Associated with This Genotype

Genotype
MGI:3581641

• Allelic Composition: Tg(WapTAg)1Knw/0
• Genetic Background: C57BL/6J-Tg(WapTAg)1Knw/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased mammary adenocarcinoma incidence ( J:53175 )

• mammary adenocarcinoma is found in multiparous females but not males or virgin females, with an average latency of 13 months

increased sarcoma incidence ( J:53175 )

• in males and virgin females, but not multiparous females, poorly differentiated soft cell sarcomas are observed frequently, usually on the trunk or extremities, with average latency of 13 months

endocrine/exocrine glands

increased mammary adenocarcinoma incidence ( J:53175 )

• mammary adenocarcinoma is found in multiparous females but not males or virgin females, with an average latency of 13 months

integument

increased mammary adenocarcinoma incidence ( J:53175 )

• mammary adenocarcinoma is found in multiparous females but not males or virgin females, with an average latency of 13 months

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
breast cancer		DOID:1612	OMIM:114480	J:53175