Phenotypes Associated with This Genotype

Genotype
MGI:3582588

• Allelic Composition: Dock7^m/Dock7^m
• Genetic Background: B6.D(Cg)-Dock7^m

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased white adipose tissue amount ( J:48831 )

• mice have 21% less inguinal adipose mass

abnormal brown adipose tissue mass ( J:45425 )

• appears to be completely absent in neonatal mice

growth/size/body

decreased body weight ( J:48831 )

• mutants weigh 15% less

decreased body length ( J:48831 )

• mutants are 8% shorter

hematopoietic system

decreased platelet ADP level ( J:45425 )

• platelet ADP levels are low

• however, the platelet count, and platelet serotonin and ATP levels are normal

homeostasis/metabolism

increased bleeding time ( J:45425 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
platelet storage pool deficiency		DOID:2223	OMIM:185050	J:45425