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Phenotypes Associated with This Genotype
Genotype
MGI:3582933
Allelic
Composition		 Bicc1jcpk/Bicc1jcpk
Genetic
Background		 involves: 101 * C3H * C57BL/6J * T STOCK
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bicc1jcpk mutation (0 available); any Bicc1 mutation (65 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
kidney cortex cyst ( J:36348 )
• cysts in the proximal and distal tubules
increased glomerular capsule space ( J:36348 )
• dilation of Bowman's space in 95% of glomeruli

liver/biliary system
abnormal bile duct morphology ( J:36348 )
• branched bile ductules are lined with hyperplastic epithelium
abnormal portal triad morphology ( J:36348 )
• the portal triad is expanded by hematopoietic cells and immature stromal cells

endocrine/exocrine glands
abnormal bile duct morphology ( J:36348 )
• branched bile ductules are lined with hyperplastic epithelium

growth/size/body
kidney cortex cyst ( J:36348 )
• cysts in the proximal and distal tubules

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
autosomal recessive polycystic kidney disease DOID:0110861 J:36348

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory