Phenotypes Associated with This Genotype

Genotype
MGI:3584120

• Allelic Composition: Crygs^Opj/Crygs⁺
• Genetic Background: involves: 102 * C3H/He * T STOCK

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Progressive cataract development in Crygs^Opj/Crygs⁺ and Crygs^Opj/Crygs^Opj mice

vision/eye

abnormal lens fiber morphology ( J:34877 )

• poor secondary fiber cell junctions

disorganized secondary lens fibers ( J:21950 )

• described as a secondary lens fiber discontinuity

cataract ( J:34877 , J:68109 )

• opacity (J:34877)

• progressive with age and less severe than homozygote (J:68109)

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 20 multiple types		DOID:0110240	OMIM:116100	J:34877 , J:68109