Analysis Tools
digestive/alimentary system
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• 5 of 6 females exhibit a reduced ano-vaginal distance
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• 2 of 3 males exhibit bowel obstructions
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renal/urinary system
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• one third of females exhibit urinary tract defects
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kidney cyst
(
J:58731
)
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• 3 of 18 females exhibit cystic kidneys
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• 2 of 3 males exhibit cystic bladders
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• 1 of 18 females exhibt a hypoplastic kidney
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• the proximal part of the penial bone is mishapen
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• the proximal part of the penial bone is smaller
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• urethra is abnormally located within the serosal layer in females
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• 1 of 18 females lack a bladder
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• 1 of 3 males exhibit a hypoplastic bladder
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• 1 of 18 females exhibit an abnormal fistula connecting the bladder and vaginal cavity
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reproductive system
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• 5 of 6 females exhibit a reduced ano-vaginal distance
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• the proximal part of the penial bone is mishapen
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• the proximal part of the penial bone is smaller
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• 1 of 18 females exhibit an abnormal fistula connecting the bladder and vaginal cavity
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• stromal tissue surrounding the cervical canals is smaller and the cervical canal is greatly reduced in size
• the columnar-to-squamosal epithelial transition that characterizes mature cervical-vaginal tissue is positioned within uterine-like stroma rather than cervical tissue
• exhibit an anterior transformation of cervical tissue to a uterine stromal phenotype
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• cervix is hypoplastic
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• 5 of 18 females exhibit enlarged, fluid-filled uterine horns
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small vagina
(
J:58731
)
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• profoundly small vaginal cavity
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growth/size/body
kidney cyst
(
J:58731
)
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• 3 of 18 females exhibit cystic kidneys
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• 2 of 3 males exhibit cystic bladders
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| hand-foot-genital syndrome | DOID:0060739 |
OMIM:140000 |
J:58731 | |
