Phenotypes Associated with This Genotype

Genotype
MGI:3590415

• Allelic Composition: Itgb2^tm1Bay/Itgb2^tm2Bay
• Genetic Background: PL.129S7-Itgb2^tm1Bay Itgb2^tm2Bay

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

dermatitis ( J:84126 )

• Background Sensitivity: develop moderate to severe psoriasiform dermatitis on the PL/J background but not on the C57BL/6J background

integument

dermatitis ( J:84126 )

• Background Sensitivity: develop moderate to severe psoriasiform dermatitis on the PL/J background but not on the C57BL/6J background

orthokeratosis ( J:84126 )

parakeratosis ( J:84126 )

acanthosis ( J:84126 )

abnormal skin condition ( J:84126 )

• Background Sensitivity: compound heterozygous mice develop chronic inflammatory skin disease on the PL/J background but not a C57BL/6J background

psoriasis ( J:84126 )

• lesions are multifocal or patchy

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
psoriasis		DOID:8893	OMIM:PS177900	J:84126