Phenotypes for Crygb MGI:3603148 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Crygb^Clapper/Crygb⁺
Genetic Background	C57BL/6J-Crygb^Clapper

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crygb^Clapper mutation (1 available); any Crygb mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Cataracts in Crygb^Clapper/Crygb^Clapper and Crygb^Clapper/Crygb⁺ mice

vision/eye

lamellar cataract ( J:100851 )

• develop lamellar cataracts, however to a less degree than seen in homozygotes

• disorganized, irregularly shaped, and smaller fibers are seen in the deeper regions of lenses

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 39 multiple types		DOID:0110236	OMIM:615188	J:100851

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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