Phenotypes Associated with This Genotype

Genotype
MGI:3604659

hm4

• Allelic Composition: Tmem79^ma/Tmem79^ma
• Genetic Background: involves: CBA/CaGr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

abnormal coat appearance ( J:24772 )

alopecia ( J:24772 )

• hairs break leading to variable degrees of baldness as mice age

matted coat ( J:24772 )

• the phenotype is obvious by 4 weeks of age, especially on the back and flanks where groups of hairs are matted at tips to form clumps

• hair does not lie flat

abnormal hair shaft morphology ( J:12995 )

abnormal hair cuticle ( J:12995 )

• cuticle shown to be permeable using fluorescent markers

• abnormal distribution of S-S linkage structure inferred as causal from experiments on normal cuticle

abnormal hair cycle ( J:12995 )

• there is no significant difference in the lengths of the first and second hair generations

• the third hair generation was shorter than normal and likely due to friction on skin exposed by progressive hair-loss