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Phenotypes Associated with This Genotype
Genotype
MGI:3608495
Allelic
Composition		 Mybpc3tm1Lcrr/Mybpc3+
Genetic
Background		 involves: 129S4/SvJae * Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mybpc3tm1Lcrr mutation (0 available); any Mybpc3 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
heart left ventricle hypertrophy ( J:101903 )
• mutant mice develop asymmetric septal hypertrophy associated with fibrosis at 10-11 month of age

growth/size/body
heart left ventricle hypertrophy ( J:101903 )
• mutant mice develop asymmetric septal hypertrophy associated with fibrosis at 10-11 month of age

muscle
heart left ventricle hypertrophy ( J:101903 )
• mutant mice develop asymmetric septal hypertrophy associated with fibrosis at 10-11 month of age

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
hypertrophic cardiomyopathy 4 DOID:0110310 OMIM:115197
 J:101903

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory