Phenotypes Associated with This Genotype

Genotype
MGI:3611211

• Allelic Composition: Psen1^tm1Dgf/Psen1^tm1Dgf; Tg(APPSWE)2576Kha/?
• Genetic Background: involves: 129 * C57BL/6 * CD-1 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

amyloid beta deposits ( J:102425 )

• accelerated onset of amyloid deposition in a gene-dosage dependent manner

• amyloid-beta deposition was widely distributed throughout the brain and spinal cord

homeostasis/metabolism

amyloid beta deposits ( J:102425 )

• accelerated onset of amyloid deposition in a gene-dosage dependent manner

• amyloid-beta deposition was widely distributed throughout the brain and spinal cord

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Alzheimer's disease		DOID:10652		J:102425