cardiovascular system
• occurs spontaneously
• cortex of kidney particularly affected
• first seen in kidneys at 6 months of age
• calcium deposits in walls of medium sized arteries with deposition along elastic fibers
• in smaller vessels, calcium deposits sometimes protrude into lumen
|
• calcium deposits appear in arteries of the renal cortex starting around 6 months of age
|
renal/urinary system
• calcium deposits appear in arteries of the renal cortex starting around 6 months of age
|
vision/eye
• calcification seen in old age
• electron dense fibers with an electron lucent core
|
homeostasis/metabolism
• at both 8 and 11 months of age
|
• at both 8 and 11 months of age
|
integument
• sparse calcified blood vessels
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
pseudoxanthoma elasticum | DOID:2738 |
OMIM:177850 OMIM:264800 |
J:105062 |