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Phenotypes Associated with This Genotype
Genotype
MGI:3615683
cx8
Allelic
Composition		 Rad50tm2Jpt/Rad50tm2Jpt
Tg(BCL2)22Wehi/0
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6JWehi * SJL/JWehi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rad50tm2Jpt mutation (0 available); any Rad50 mutation (53 available)
Tg(BCL2)22Wehi mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:103922 )
• although mutants succumb to anemia, it is significantly later than in homozygous Rad50tm2Jpt mice, with all dying by 7.5 months of age

hematopoietic system
anemia ( J:103922 )
• although mutants succumb to anemia, it is significantly later than in homozygous Rad50tm2Jpt mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory