Phenotypes Associated with This Genotype

Genotype
MGI:3617390

• Allelic Composition: Pkd1^tm2.1Ggg/Pkd1^tm2.1Ggg
• Genetic Background: involves: 129S4/SvJae * Black Swiss * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:103719 )

• stage not specified, although embryos are recovered at E15.5

renal/urinary system

kidney cyst ( J:103719 )

endocrine/exocrine glands

pancreas cyst ( J:103719 )

homeostasis/metabolism

abnormal fluid regulation ( J:103719 )

• phenotype is stated to be similar to that of compound heterozygous Pkd1^tm1Ggg and Pkd1^tm2.1Ggg mice, however no data is presented in J:103719

cardiovascular system

hemorrhage ( J:103719 )

• phenotype is stated to be similar to that of compound heterozygous Pkd1^tm1Ggg and Pkd1^tm2.1Ggg mice, however no data is presented in J:103719

growth/size/body

pancreas cyst ( J:103719 )

kidney cyst ( J:103719 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
polycystic kidney disease 1		DOID:0110858	OMIM:173900	J:103719