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Phenotypes Associated with This Genotype
Genotype
MGI:3620239
cx2
Allelic
Composition		 Prkdcscid/Prkdcscid
Tg(CSF2)2Ygy/0
Tg(IL3)1Ygy/0
Genetic
Background		 CB17.Cg-Prkdcscid Tg(CSF2)2Ygy Tg(IL3)1Ygy
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkdcscid mutation (177 available); any Prkdc mutation (417 available)
Tg(CSF2)2Ygy mutation (2 available)
Tg(IL3)1Ygy mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal response to transplant ( J:94302 )
• engraftment of porcine bone marrow cells after bone marrow transplant into irradiated transgenic SCID mice is achieved and porcine hematopoesis is maintained at 7 weeks post-transplant with less efficiency than in mice also expressing the KITLG transgene

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory