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Phenotypes Associated with This Genotype
Genotype
MGI:3621024
cx4
Allelic
Composition		 Etv1tm2Tmj/Etv1+
Etv4tm1Arbr/Etv4+
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etv1tm2Tmj mutation (0 available); any Etv1 mutation (44 available)
Etv4tm1Arbr mutation (0 available); any Etv4 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal somatic sensory system morphology ( J:107207 )
• the interosseous nerve is present but thinner than in wild-type mice
decreased pacinian corpuscle number ( J:107207 )
• 20% decrease in pacinian corpuscle numbers in the crus at P0-P1
small pacinian corpuscles ( J:107207 )
• remaining corpuscles are smaller than wild-type but structurally similar

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory