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Phenotypes Associated with This Genotype
Genotype
MGI:3623006
hm1
Allelic
Composition		 Ryr3tm2Tno/Ryr3tm2Tno
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ryr3tm2Tno mutation (1 available); any Ryr3 mutation (261 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hyperactivity ( J:34908 )
• homozygous mutants appear restless compared to littermates
increased locomotor activity ( J:34908 )
• mutants exhibit approximately 2-fold greater locomotor activity than heterozygotes or wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory