Phenotypes Associated with This Genotype

Genotype
MGI:3623010

ht3

• Allelic Composition: Ryr3^tm1Tno/Ryr3⁺
• Genetic Background: involves: 129S4/SvJae * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired passive avoidance behavior ( J:61004 )

• heterozygous mice show intermediate passive avoidance performance between homozygotes and wild-type

abnormal contextual conditioning behavior ( J:61004 )

• after a foot shock on Day 1, heterozygotes show an intermediate decrease in locomotor activity on Day2 compared to nulls and wild-type.

abnormal spatial learning ( J:61004 )

• heterozygotes display an intermediate level of spontaneous alternation behavior in a Y-maze test with respect to wild-type and nulls.