Phenotypes for Smad4 Tg(Hoxb7-cre)1Rob MGI:3628945 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Smad4^tm1Rob/Smad4^tm1.1Rob Tg(Hoxb7-cre)1Rob/0
Genetic Background	involves: 129S/SvEv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smad4^tm1.1Rob mutation (0 available); any Smad4 mutation (48 available)
Smad4^tm1Rob mutation (0 available); any Smad4 mutation (48 available)
Tg(Hoxb7-cre)1Rob mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:108109 )

• by 8 weeks of age 3 of 8 mice had died

renal/urinary system

renal/urinary system phenotype ( J:108109 )

N	• at E16.5 kidneys appear morphologically similar to control mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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