behavior/neurological
• traveled a significantly shorter distance in the open field
• spent significantly less time in the center of the open field
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• showed exaggerated immobility in response to repeated, but not acute, exposure to the tail suspension test
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• buried significantly fewer marbles than control
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• male mutant mice spend more time in an empty cage than in a cage with a strange mouse in the sociability choice test; female mutant mice did not behave differently than controls
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
autism spectrum disorder | DOID:0060041 | J:192363 |