hematopoietic system
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3, but normal colony growth occurs in response to GM-CSF
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• Il3 alone does not support granulocyte/macrophage colony formation in bone marrow cells from A/J mice but does in bone marrow from C57BL/6 controls; costimulation with both Il3 and SCF increases the number of colonies formed compared to SCF alone
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immune system
• Il3 alone does not support granulocyte/macrophage colony formation in bone marrow cells from A/J mice but does in bone marrow from C57BL/6 controls; costimulation with both Il3 and SCF increases the number of colonies formed compared to SCF alone
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