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Phenotypes Associated with This Genotype
Genotype
MGI:3687241
cx7
Allelic
Composition		 Mapk1tm1Hed/Mapk1tm1Hed
Mapk3tm1Gpg/Mapk3tm1Gpg
Tg(TcraTcrb)1100Mjb/0
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapk1tm1Hed mutation (0 available); any Mapk1 mutation (43 available)
Mapk3tm1Gpg mutation (1 available); any Mapk3 mutation (26 available)
Tg(TcraTcrb)1100Mjb mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased thymocyte number ( J:113280 )
• population is lower than in Mapk1-deficient mice with Tg(CD4-cre)1Cwi or with transgene and Mapk3 deficiency

hematopoietic system
decreased thymocyte number ( J:113280 )
• population is lower than in Mapk1-deficient mice with Tg(CD4-cre)1Cwi or with transgene and Mapk3 deficiency

endocrine/exocrine glands
decreased thymocyte number ( J:113280 )
• population is lower than in Mapk1-deficient mice with Tg(CD4-cre)1Cwi or with transgene and Mapk3 deficiency

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory