mortality/aging
|
• die by E15.5
|
cardiovascular system
|
• outflow tract seems to be more centrally located and fails to separate
|
|
• exhibit a common arterial trunk in which there is no separate aorta and pulmonary artery, but a single vessel that emerges from the right ventricle
|
|
• exhibit thickening of the mitral valve (dysplasia)
|
|
• exhibit atrial septal defect primum
|
|
• exhibit ventricular septal defects
|
craniofacial
|
• palatal shelves fail to elevate at E15.5
|
homeostasis/metabolism
skeleton
|
• exhibit incomplete fusion of the sternum at E15.5
|
digestive/alimentary system
|
• palatal shelves fail to elevate at E15.5
|
growth/size/body
|
• palatal shelves fail to elevate at E15.5
|
omphalocele
(
J:112274
)
|
• exhibit umbilical hernia and show delayed resorption of the hernia
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
periventricular nodular heterotopia | DOID:0050454 |
OMIM:300049 OMIM:608097 OMIM:608098 OMIM:612881 OMIM:615544 |
J:112274 |