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Phenotypes Associated with This Genotype
Genotype
MGI:3689510
cx3
Allelic
Composition
Adra1atm1Pcs/Adra1atm1Pcs
Adra1btm1Cta/Adra1btm1Cta
Genetic
Background
B6.129-Adra1btm1Cta Adra1atm1Pcs
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adra1atm1Pcs mutation (1 available); any Adra1a mutation (32 available)
Adra1btm1Cta mutation (1 available); any Adra1b mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• myocyte cross-sectional area and surface area are 25% smaller in males than in wild-type
• hearts are smaller in males, but not females, due to smaller myocytes

muscle
• myocyte cross-sectional area and surface area are 25% smaller in males than in wild-type


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory