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Phenotypes Associated with This Genotype
Genotype
MGI:3693491
Allelic
Composition		 Tg(PSEN1H163R)G9Btla/0
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(PSEN1H163R)G9Btla mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
amyloid beta deposits ( J:58050 )
• lower levels of Abeta1-42 amyloid peptide accumulate compared to double transgenic mice

homeostasis/metabolism
amyloid beta deposits ( J:58050 )
• lower levels of Abeta1-42 amyloid peptide accumulate compared to double transgenic mice

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
Alzheimer's disease DOID:10652 J:58050
Alzheimer's disease 3 DOID:0110042 OMIM:607822
 J:58050

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory