Phenotypes Associated with This Genotype

Genotype
MGI:3697171

• Allelic Composition: Ass1^fold/Ass1^fold
• Genetic Background: involves: C57BL/6JEiJ * P/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:117339 )

• no homozygotes survive long enough to breed

postnatal lethality ( J:117339 )

• most homozygotes die by 3 weeks of age

growth/size/body

decreased body size ( J:117339 )

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:117339 )

N • ABR assessment shows normal hearing

vision/eye

vision/eye phenotype ( J:117339 )

N • normal iris, lens and retinas by opthalmoscopic examination

integument

delayed hair appearance ( J:117339 )

sparse hair ( J:117339 )

• enough hair grows in by 3 weaks of age for a sparse coat

abnormal hair shaft morphology ( J:117339 )

• the hair follicle does not produce a normal hair fiber

abnormal hair follicle development ( J:117339 )

wrinkled skin ( J:117339 )

• skin is wrinkled by 2 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
citrullinemia		DOID:9273		J:165341