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Phenotypes Associated with This Genotype
Genotype
MGI:3699097
Allelic
Composition
Htttm1.1Tna/Htt+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Htttm1.1Tna mutation (0 available); any Htt mutation (178 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• exhibit an increase in glial fibrillary acidic protein (GFAP)-positive cells in the substantia nigra and the globus pallidus at 40 weeks of age, indicating astrocytosis

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Huntington's disease DOID:12858 OMIM:143100
J:76017


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory