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Phenotypes Associated with This Genotype
Genotype
MGI:3699180
cn4
Allelic
Composition		 Gba1tm1Clk/Gba1tm1.1Clk
Tg(EIIa-cre)C5379Lmgd/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gba1tm1.1Clk mutation (2 available); any Gba1 mutation (45 available)
Gba1tm1Clk mutation (1 available); any Gba1 mutation (45 available)
Tg(EIIa-cre)C5379Lmgd mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal enzyme/coenzyme activity ( J:117763 )
• tissue glucocerebrosidase activity is reduced to ~30% of control levels except in spleen (38%) and peripheral white cells (45%)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory