Phenotypes for Fos Trp53 MGI:3700990 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Fos^tm1Wag/Fos^tm1Wag Trp53^tm1Tyj/Trp53⁺
Genetic Background	involves: 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fos^tm1Wag mutation (0 available); any Fos mutation (43 available)
Trp53^tm1Tyj mutation (12 available); any Trp53 mutation (244 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased rhabdomyosarcoma incidence ( J:89283 )

• double mutants develop facial and orbital tumors with lower penetrance than in double homozygous mice

muscle

increased rhabdomyosarcoma incidence ( J:89283 )

• double mutants develop facial and orbital tumors with lower penetrance than in double homozygous mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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