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Phenotypes Associated with This Genotype
Genotype
MGI:3702617
cx4
Allelic
Composition		 Sox1tm1Vep/Sox1tm1Vep
Sox2tm1Vep/Sox2+
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox1tm1Vep mutation (0 available); any Sox1 mutation (13 available)
Sox2tm1Vep mutation (0 available); any Sox2 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory cortex morphology ( J:99610 )
• olfactory tubercle (OT) region is compacted in absence of many Sox1 neurons
• neurons expressing Sox1 from the Sox2 locus migrate to the OT in absence of endogenous Sox1 expression; striatal bridges form

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory