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Phenotypes Associated with This Genotype
Genotype
MGI:3711108
Allelic
Composition		 Tg(HLA-A/H2-D/B2M)1Dvs/0
Genetic
Background		 NOD/ShiLtDvs-Tg(HLA-A/H2-D/B2M)1Dvs
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(HLA-A/H2-D/B2M)1Dvs mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to autoimmune diabetes ( J:121685 )
• females develop accelerated type I diabetes through 30 weeks of age, compared to NOD controls

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
type 1 diabetes mellitus DOID:9744 OMIM:222100
 J:121685

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory