Phenotypes Associated with This Genotype

Genotype
MGI:3711148

• Allelic Composition: Plp1^jp-rsh/Y
• Genetic Background: involves: C3H * C57BL/6 * STOCK Rb(1.3)1Bnr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal locomotor coordination ( J:121540 )

♂ • mice performed initially poorly but eventually were indistinguishable from controls

cellular

increased apoptosis ( J:121540 )

♂ • average tunnel count of 37+/-4

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Pelizaeus-Merzbacher disease		DOID:3210	OMIM:312080	J:121540