Phenotypes Associated with This Genotype

Genotype
MGI:3711151

• Allelic Composition: Plp1^jp-msd/Y
• Genetic Background: involves: BALB/c * C3H * C57BL/6 * C57BL/10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:121540 )

♂ • mice begin to die at P24 and are all dead by P30

cellular

increased apoptosis ( J:121540 )

♂ • average tunnel count of 74+/-4

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Pelizaeus-Merzbacher disease		DOID:3210	OMIM:312080	J:121540