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Phenotypes Associated with This Genotype
Genotype
MGI:3713302
Allelic
Composition		 Gcktm2Mgn/Gcktm2Mgn
Genetic
Background		 129S6/SvEvTac-Gcktm2Mgn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gcktm2Mgn mutation (2 available); any Gck mutation (63 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:121910 )
• mice die within a few days of birth from hyperglycemia

homeostasis/metabolism
hyperglycemia ( J:121910 )
• severe hyperglycemia is displayed

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
maturity-onset diabetes of the young type 2 DOID:0111100 OMIM:125851
 J:121910

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory