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Phenotypes Associated with This Genotype
Genotype
MGI:3713801
hm1
Allelic
Composition		 Otptm1Asim/Otptm1Asim
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Otptm1Asim mutation (1 available); any Otp mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dopaminergic neuron morphology ( J:122105 )
• dopanergic neurons in group A11 are mis-specified or lose their specificity as shown by the loss of tyrosine hydroxylase, Nkx2.1, Otx and AADC staining at E11.5 and E15.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory