Phenotypes Associated with This Genotype

Genotype
MGI:3714862

• Allelic Composition: Cdh23^v-ngt/Cdh23^v-ngt
• Genetic Background: involves: ICR * MSM

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

abnormal cochlear outer hair cell morphology ( J:69028 )

• incomplete loss of outer hair cells is seen at 7 weeks of age

abnormal outer hair cell stereociliary bundle morphology ( J:69028 )

• irregular arrays of stereocilia are seen at 7 weeks of age

deafness ( J:69028 )

behavior/neurological

absent pinna reflex ( J:69028 )

head shaking ( J:69028 )

circling ( J:69028 )

nervous system

abnormal cochlear outer hair cell morphology ( J:69028 )

• incomplete loss of outer hair cells is seen at 7 weeks of age

abnormal outer hair cell stereociliary bundle morphology ( J:69028 )

• irregular arrays of stereocilia are seen at 7 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Usher syndrome type 1D		DOID:0110831	OMIM:601067	J:174130