Phenotypes for Adcy3 Omp MGI:3714863 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Adcy3^tm1Drs/Adcy3^tm1Drs Omp^tm1Mom/Omp⁺
Genetic Background	involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adcy3^tm1Drs mutation (0 available); any Adcy3 mutation (43 available)
Omp^tm1Mom mutation (2 available); any Omp mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:122528 )

• most glomeruli, including those in the necklace and Grueneberg, are reduced and loosely organized

• however, epithelia have normal amounts of mature olfactory sensory neurons

abnormal olfactory nerve morphology ( J:122528 )

• from P15, Omp+ mature neurons are absent from the dorsocaudal part of the olfactory bulb

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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