Phenotypes for Adcy3 Or8a1b MGI:3714866 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Adcy3^tm1Drs/Adcy3^tm1Drs Or8a1b^tm4Mom/Or8a1b⁺
Genetic Background	involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adcy3^tm1Drs mutation (0 available); any Adcy3 mutation (43 available)
Or8a1b^tm4Mom mutation (1 available); any Or8a1b mutation (35 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:122528 )

• glomeruli structure is irregular

abnormal olfactory nerve morphology ( J:122528 )

• on the median and lateral sides of the bulb, fewer Olfr160+ neurons form large glomeruli as in wild-type mice

• fewer Olfr160+ neurons are present (197+/-40 compared to 213+/-51 in wild-type mice)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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