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Phenotypes Associated with This Genotype
Genotype
MGI:3714930
cx1
Allelic
Composition		 Map2k1tm1Chrn/Map2k1tm1Chrn
Map2k2tm1Chrn/Map2k2tm1Chrn
Tg(KRT14-RAF1/ESR1)1Pkha/?
Genetic
Background		 involves: 129/Sv * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map2k1tm1Chrn mutation (1 available); any Map2k1 mutation (94 available)
Map2k2tm1Chrn mutation (1 available); any Map2k2 mutation (37 available)
Tg(KRT14-RAF1/ESR1)1Pkha mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
skin hypoplasia ( J:122484 )
• following tamoxifen treatment, mice have increased epidermal hypoplasia and increased cell death

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory