Phenotypes Associated with This Genotype

Genotype
MGI:3718059

ot9

• Allelic Composition: Ts(17¹⁶)65Dn/0
• Genetic Background: involves: C3H/HeJ * C57BL/6 * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

increased brain size ( J:121764 )

decreased Purkinje cell number ( J:121764 )

• Purkinje cell density is reduced to 90% of that in control mice

abnormal cerebellar granule cell morphology ( J:121764 )

• granule cell density is reduced to 76% of that in control mice

small cerebellum ( J:121764 )

• cerebellar volume is reduced to 88% of that in control mice

behavior/neurological

abnormal spatial learning ( J:121764 )

• mice show impairment in a Morris water maze test

growth/size/body

decreased body weight ( J:121764 )