Phenotypes Associated with This Genotype

Genotype
MGI:3720210

tg4

• Allelic Composition: Tg(Thy1-MAPT)1Vln/0
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal axon morphology ( J:100972 )

• dilated axons are observed in brain and spinal cord

behavior/neurological

impaired coordination ( J:100972 )

• compared to wild-type mice, mutants are 13 times more likely to fall off of a rotating rod in a rotarod test

abnormal locomotor activation ( J:100972 )

• heterozygous mice display higher swimming speeds than wild-type mice