Phenotypes Associated with This Genotype

Genotype
MGI:3722926

• Allelic Composition: Alpl^Hpp/Alpl^Hpp
• Genetic Background: involves: BALB/cAnN * C3H/HeH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:122319 )

• plasma ALP levels are very low, but detectable in 5 week old homozygotes

• ALP levels decrease further with age at a similar rate to controls

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
adult hypophosphatasia		DOID:0110913	OMIM:146300	J:122319