Phenotypes Associated with This Genotype

Genotype
MGI:3723222

• Allelic Composition: Trps1^tm1.1Shiv/Trps1⁺
• Genetic Background: either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

arched palate ( J:80615 )

• presence of an abnormally arched (but not cleft) palate in adults

skeleton

kyphoscoliosis ( J:80615 )

• seen by 3 months of age

decreased bone mineral density ( J:80615 )

• femurs show reductions in whole and especially trabecular bone volume density

digestive/alimentary system

arched palate ( J:80615 )

• presence of an abnormally arched (but not cleft) palate in adults

integument

decreased hair follicle number ( J:80615 )

• fewer numbers of hair follicles present per unit length of dorsal skin surface in neonates, however, defects in quantitative or qualitative aspects of the pelage are not evident in adults

growth/size/body

arched palate ( J:80615 )

• presence of an abnormally arched (but not cleft) palate in adults

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
trichorhinophalangeal syndrome type I		DOID:14743	OMIM:190350	J:80615