Phenotypes Associated with This Genotype

Genotype
MGI:3758740

hm1

• Allelic Composition: Galk1^tm1Stb/Galk1^tm1Stb
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:63743 )

N • on a 40% galactose or 40% glucose diet, mice do not develop cataracts

homeostasis/metabolism

abnormal homeostasis ( J:63743 )

• on a 40% glucose diet, mice exhibit detectable accumulation of galactose and galactitol in liver, brain, and kidney in contrast to wild-type animals

• on a 40% galactose diet, markedly elevated galactitol levels are observed in liver and kidney in mutants and wild-type, but levels are higher in mutants